We emphasize that the notion of self-assembly has to be used with care. Individual vesicles may emerge autonomously in according mixtures of lipids and water. This doesn't hold anymore for vesicle assemblies, at least not for vesicles in the micro-meter range. This, because the thermal or Brownian motion is too small to achieve the necessary collision frequency between the components. During PACE several methods for "assisted" self-assembly were developed. The "self" in self-assembly refers to the autonomous and local control of the assembly process, but not anymore to the autonomous placement of components.